MARIJUANA-ASSOCIATED CYSTIC LUNG DISEASE

TOPIC: Diffuse Lung Disease TYPE: Fellow Case Reports INTRODUCTION: It has been well established that marijuana smoking is associated with cystic lung disease. We bring forth a case of vaping THC containing product and was disease which partially reversed after full cessation vaping. CASE PRESENTATION: A 20 y/o Caucasian male no medical history presented for evaluation his abnormal CT chest. He had an extensive 10 PPY tobacco use the patient quit 3 years ago started as substitute. used solvent based contained butane among many other solvents. admitted to buying illegal additives. On chest there were scattered foci within lungs largest left lower lobe air-fluid level adjacent groundglass opacities consolidation. Since chest, months ago, stopped Patient also negative rheumatological vasculitis work-up. Currently he only smokes 1/2 ounce "flower" (plant-based marijuana) day 4 "dabs" (marijuana concentrates) on weekends. denied using any recreational drugs. symptoms shortness breath or physical limitations due breathing.Upon returning back clinic later, pulmonary function test (PFT) repeat The PFT revealed obstruction decreased FEV1/FVC ratio mild scooping expiratory limb flow volume loop. Additionally, significantly diffusion capacity. scan dominant lesion in size residual focal nodular consolidation this region. However, now multiple new perivascular ground-glass some demonstrate internal thin wall cavitation.Given subsequent partial resolution PFT, diagnosed extensively counselled cessation. DISCUSSION: Our not re-demonstrated existing association between smoking, but brought another complication solvents resolve Clinicians should be vigilant about getting strictly advising products can lead deteriorate well. CONCLUSIONS: This brings interesting link Therefore, clinicians have thorough investigation their history, especially when encountering young patients REFERENCE #1: Ribeiro L, Ind PW. Marijuana lung: hysteria cause concern?. Breathe (Sheff). 2018;14(3):196-205. doi:10.1183/20734735.020418 #2: Mishra R, Patel Khaja M. Cannabis-induced bullous leading pneumothorax: report literature review. Medicine (Baltimore). 2017;96(19):e6917. doi:10.1097/MD.0000000000006917 #3: LI, Effect cannabis respiratory symptoms: structured NPJ Prim Care Respir Med. 2016;26:16071. Published 2016 Oct 20. doi:10.1038/npjpcrm.2016.71 DISCLOSURES: No relevant relationships by Jalal Damani, source=Web Response